Since the government in Płock was taken over by the German civilian administration, it began brutal persecution of Jews. The city synagogue was turned into a car workshop, and the old and new cemeteries were devastated and the matzevot were used for making paving stones. Moreover, plunder of private Jewish property was started. At that time, the city was included in Regierungsbezirk Zichenau (Ciechanów Region) – East Prussia, and the Germans called Płock Schröttersburg.

The situation worsened when a ghetto was established in Płock on September 1, 1940 with about 10,000 Jews locked there.  Numerous acts of terror and executions began. With particular ferocity, the Germans got rid of the old Jewish people from the town and its vicinity. To achieve that, they prepared the great deportation of Jews, known under the name “Tempo”. It was supervised by the Umwandererzentralstelle (Resettlement Center) in Berlin. The census of the Jewish population started.

To prevent the elderly from being a ballast during the deportation, at the end of 1940, all the patients of the Jewish Retirement Home were murdered. Then, on the order of the Germans, the Płock Judenrat presented a list of old, sick and infirm people. They were taken away and probably murdered in the Brwilski Forests, about 10 km from the city. There, 7 Jews who had been treated in the care facility of the Congregation of the Passionist Sisters were also executed.

The German occupier started the resettlement from Poles. It lasted from February to May 1940, but a year later, on February 17, 1941, about 5,000 people Poles were expelled from the city at one time. They were sent to the resettlement camp in Działdowo.

A few days later, on the night of February 20-21, 1941 the deportation of the Płock ghetto began. The Jewish population was beaten and driven to trucks. Many people did not manage to get dressed, and those who grabbed their luggage on the run had to leave it at the entrance to the cars. The SS men killed on the spot all people who were sick and disabled.

The first displacement included about 4 thousand Jews. Just like the Poles before, they were taken to the camp in Działdowo. After its liquidation, the Germans directed the Płock Jews to the Radom region and sent them into 20 localities. All they died in the Holocaust.